Pharma

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Featured Products

Dr. Paul Lohmann logo

Active Pharmaceutical Ingredients (APIs)

In 1994, Dr. Paul Lohmann® was one of the first German raw material manufacturers to obtain the GMP (Good Manufacturing Practice) certification.
Since then the company has regularly been inspected by the German health authorities and has maintained this high-level certification although the quality requirements have constantly risen.

Based on this solid foundation of quality, Dr. Paul Lohmann® is capable of manufacturing and documenting APis (Active Pharmaceutical Ingredients).

A broad range of different APis are manufactured in our GMP certified manufacturing sites in Emmerthal and LOneburg.  These APis are used in medicines for the following therapeutic areas:

  • Orthopedics
  • Hematology
  • Cardiology
  • Gastroenterology
  • Immunology
  • Nephrology
  • Neurology

Product Line Low in Endotoxins

Dr. Paul Lohmann® also offers APIs even in low in endotoxin qualities. These APis are applied in parenteral preparations such as infusions, injections or ophthalmological dosage forms.

These highest regulatory and quality requirements are fulfilled by a QbD (Quality by Design approach). A dedicated purpose-built GMP certified plant ensures the production of APis meeting highest purity requirements.

Please also see our brochure:  Mineral Salts low in Endotoxins

See more details in the brochure alongside.
See more details in the brochure below.
API_DNR266_RevB
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Dr. Paul Lohmann logo

Minerals as Excipients

The major component of ingredients in final pharmaceutical products, such as tablets or
capsules, is not the active ingredient itself, it is the excipient.

Excipients assist in the administration of an ‘active’ substance that typically may not be easily administered or absorbed by the patient.

Mineral Salts as excipients are of specific importance, since they largely determine the structure
of solid dosage forms and stabilize the chemical properties in liquid pharmaceutical forms.

Excipients have well-defined functions, which significantly influence the processability, stability
and control the release of the drug product.  Therefore, the selection of excipients is crucial to ensure that the drug substance is stable and has desired pharmacokinetic properties, adhering to strict standards and regulations.

Produced for Functionality

Excipients fall into several broad processing categories for functionalities.

  • Bulking agents make the dosage form larger in size, so that it becomes easier to manufacture and for patients to handle.
  • Binders, which are also used in our granules for direct compression (DC), are utilized to facilitate the granulation process to make powders easier to compress.
  • Glidants help the powders flow finally from the hopper to the capsule or tablet cavity and minimize friction and cohesion between particles.
  • Lubricants are often used in combination with glidants to reduce the stickiness of powders or granules to the dyes or punches during compression.

A pH-adjuster modifies the pH-value in order to stabilize the drug substance in parenteral dosage forms or optimize the taste and disintegration in oral effervescent tablets.

Due to the chemical nature of Mineral Salts, Dr. Paul Lohmann® products are mostly used for functionalities beyond the above mentioned examples.

Since Dr. Paul Lohmann® Mineral Salts are an integral component of pharmaceutical drugs, its excipients fulfill IPEC (International Pharmaceutical Excipients Council} and ISO 9001 guidelines.

Product Line Low in Endotoxins

Dr. Paul Lohmann® offers excipients even in Low in Endotoxins pharmaceutical grades which are applied in parenteral preparations such as infusions or injections.

These highly sensitive routes of administration require highest purity standards, which are fulfilled by our Quality by Design (ObD) approach.  A dedicated purpose built GMP certified plant ensures the production of excipients meeting highest purity.

Biopharmaceuticals, vaccines and blood plasma derived medicines utilize Phosphates and Citrates as excipients to achieve the required pH-value or EDT As to stabilize the drug substance. Dr. Paul Lohmann® Low in Endotoxin Mineral Salt excipients enable a seamless integration into the production process and reduce process complexity.

Please also see our brochure:  Mineral Salts low in Endotoxins

See more details in the brochure alongside.
See more details in the brochure below.
Excipients_DNR274_RevA
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Fytexia logo

Sinetrol® – Fat Loss for the Long Term

Sinetrol Active Living by Fytexia
Sinetrol® is a natural combination of citrus polyphenols proven to provide the benefits of adipose beiging to increase energy expenditure, and thus amplifying lipolysis and reducing excess fat mass. Sinetrol® improves long-term body composition. Supported with published clinical trials on Asian and Caucasian subjects.

Sinetrol® – Key features

  • Proven mechanism of action: lipolysis enhancer providing adipose beiging benefits
  • Increase in resting energy expenditure
  • Rebalanced body composition: significant reduction of body fat mass without lean mass loss
  • Significant results on body weight, waist and hip lines
  • Long-lasting benefits: subjects continue to benefit from adipose beiging after the end of the supplementation4

Science supporting Sinetrol®

More than 10 years of research have been conducted to support the characterisation, mechanism of action and clinical benefits of Sinetrol® on body composition.

Sinetrol® is a botanical ingredient studied in over 300 subjects and its benefits have been demonstrated using gold-standard methodology during interventional studies with follow-up.

Find complete details in the brochures below

PDF Brochures

Sinetrol - Adipose beiging benefits - Brochure
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Sinetrol® - Fat loss for the long-term - Brochure
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Sinetrol Active Living [Concept to formulate] by Fytexia
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Balchem logo

TRAACS® (The Real Amino Acid Chelate System)

Chelated Minerals – Nature’s Way

Essential for optimal health, minerals are the unsung heroes within. Unlike commonplace, inorganic minerals , Albion® mineral amino acid chelates emulate nature’s packaging, optimizing absorption for optimal benefits.
The term “chelate” traces its origin to the Greek word “chele,” meaning “claw.”  Just like a set of claws wrapping around the metal, Albion® chelates form robust bonds with ligand molecules, rendering unique nutritional attributes: a molecular weight under 800 Daltons, a neutral charge, and exceptional stability, preventing unwanted reactions.

This composition facilitates efficient metabolism, leading to improved nutrient absorption and heightened nutrient density.

Bioavailability – Albion’s® Pledge

Not all minerals are created equal.  While many supplements fall short, Albion® stands tall, wrapping minerals in nature’s design for maximum absorption.  Our secret?  Amino acids, like the bond between glycine and magnesium forming magnesium bisglycinate, ensuring nutrients reach where they’re most needed.

Albion® Minerals – Beyond Excellence

Safety and quality are our pledges.  Beyond superior bioavailability, we stand for purity and global compliance.

Albion’s® commitment to quality starts with carefully selected, pure ingredients sourced through approved manufacturers.  Our rigorous testing ensures halal, kosher, and non-GMO compliance.  Additionally, chelated minerals don’t need ionization and are not pH dependent.

On the other hand, non-chelated mineral compounds may compromise the integrity of essential nutrients, including vitamins A and E, ascorbic acid, specific B vitamins, and certain medicinal agents.

Why Choose Albion® Minerals?

  • Experience Pioneered:  From our inception in 1956 to the present, leading the chelation frontier.
  • Bioavailability Perfected:  Natural packaging, optimal absorption, and proven stability.
  • Scientifically Validated:  With over 160 publications, our products are more than just claims.
See more details in the brochure alongside.
See more details in the brochure below.
The Power of Winerals_Albion Minerals
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